Research demonstrates the predictive value of nutritional risk indexes for frailty progression in older adults, indicating their clinical relevance.
As malnutrition is a significant risk factor for frailty, both the PNI and GNRI are valuable tools in assessing the nutritional risk and had shown strong association in detecting frailty status and in predicting frailty risk, their further integration into clinical use is promising.
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Hsu et al. (2026) studied this question.
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