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January 29, 2026PLoS ONEOpen Access

Correction: Design of a multi-epitope recombinant BCG vaccine targeting Brucella OMP31, LptE and VirB2 in immunoinformatics approaches

The PLOS One Staff

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Key Points

The aim is to develop a multi-epitope recombinant BCG vaccine against Brucella by using immunoinformatics approaches.
Utilized computational immunoinformatics for epitope prediction.
Targeted Brucella proteins OMP31, LptE, and VirB2 in vaccine design.
Evaluated potential immunogenicity and efficacy of the vaccine.
Identified multiple epitopes for effective immune response against Brucella.
Enhanced vaccine design leads to higher anticipated immune protection.
Demonstrated feasibility of using immunoinformatics in vaccine development.

Implication

Correction reports immunoinformatics development of a BCG vaccine targeting Brucella, suggesting improved protective strategies.

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Cite This Study

The PLOS One Staff (2026) studied this question.

synapsesocial.com/papers/6980fdc7c1c9540dea80f723 https://doi.org/10.1371/journal.pone.0342000

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Immunoinformatics design and in vitro evaluation of dendritic cell-targeting brucellosis multi-epitope vaccine based on Omp28 and GroELIn Vitro Study · 2026
2In silico designed novel multi-epitope mRNA vaccines against Brucella by targeting extracellular protein BtuB and LptD2024 · 32 citations
3Design of a multi-Epitope mRNA vaccine against Brucella type IV secretion system using reverse vaccinology and immunogenicity approaches2025 · 9 citations
4Development of REC1: A Reverse Vaccinology-Derived Multi-Epitope Vaccine Candidate Against BrucellosisOriginal Research · 2026
5Immunogenic effects of a combined recombinant protein formulation based on Brucella Omp19, Omp2b, Omp31, and BP26Original Research · 2026

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Reverse Vaccinology and Immune Simulation of a Novel Multiepitope Vaccine Targeting Brucella Virulence2026
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Extracellular vesicle–guided antigen selection enables a protective multiepitope vaccine against Brucella abortus2026

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