ROS-Responsive Antioxidant Hydrogel with Immunomodulatory Activity for Promoting Diabetic Wound Healing

Yurao Liu; Qianqian Yang; Ling Zhang; Qiyue Lu; Yuhang Li; Haisong Zhang; Chunfang Zhang; Pingli Wu

doi:10.1039/d6bm00018e

January 1, 2026Biomaterials Science

ROS-Responsive Antioxidant Hydrogel with Immunomodulatory Activity for Promoting Diabetic Wound Healing

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Key Points

The aim is to develop a ROS-responsive hydrogel that reduces oxidative stress to improve healing in diabetic wounds.
Developed a ROS-responsive antioxidant hydrogel.
Evaluated the hydrogel's effects on oxidative stress in wound healing models.
Assessed the immunomodulatory activity of the hydrogel.
The hydrogel significantly reduced oxidative stress in diabetic wounds.
Improved wound healing rates were observed compared to controls.
Enhanced immunomodulatory responses were identified with the hydrogel application.

Implication

Demonstrates a novel hydrogel enhances wound healing in diabetes, suggesting a new treatment option.

Abstract

The accumulation of reactive oxygen species (ROS) in the microenvironment of diabetic wounds can trigger oxidative stress and hinder wound healing. This study developed a novel ROS-responsive antioxidant hydrogel relying...

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6980fdc7c1c9540dea80f895 https://doi.org/10.1039/d6bm00018e

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ROS-Responsive Antioxidant Hydrogel with Immunomodulatory Activity for Promoting Diabetic Wound Healing

Key Points

Implication

Abstract

Discussion

Cite This Study

ROS-Responsive Antioxidant Hydrogel with Immunomodulatory Activity for Promoting Diabetic Wound Healing

Key Points

Implication

Abstract

Discussion

Cite This Study

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