PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 2, 2026Anticancer Research0 citations

Amlodipine Suppresses Lung Metastasis by Increasing Cell Stiffness

View Full Paper
TUTeruya UchiyamaKAKUNIHIRO ASANUMAKKKouji Kita

Key Points

  • The aim is to investigate how amlodipine affects tumor cell stiffness and its impact on lung metastasis.
  • Evaluated the effects of amlodipine on tumor cell properties in vitro.
  • Measured cell stiffness using appropriate mechanical assessments.
  • Assessed lung metastasis in relevant experimental models.
  • Amlodipine treatment significantly increased tumor cell stiffness.
  • Lung metastasis was significantly reduced following treatment with amlodipine.

Abstract

Amlodipine could increase tumor cell stiffness and significantly reduce lung metastasis.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Uchiyama et al. (2026) studied this question.

synapsesocial.com/papers/6980fe13c1c9540dea80fe29https://doi.org/10.21873/anticanres.17979
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Amlodipine Inhibition of Serum-, Thrombin-, or Fibroblast Growth Factor-Induced Vascular Smooth-Muscle Cell Proliferation1998 · 67 citations
  2. 2AMLODIPINE PREVENTS MONOCROTALINE‐INDUCED PULMONARY ARTERIAL HYPERTENSION AND PROLONGS SURVIVAL IN RATS INDEPENDENT OF BLOOD PRESSURE LOWERING2007 · 30 citations
  3. 3Novel Mechanisms of the Antiproliferative Effects of Amlodipine in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats2002 · 33 citations
  4. 4Long acting calcium antagonist amlodipine prevents left ventricular remodeling after myocardial infarction in rats1998 · 28 citations
  5. 5Haemodynamic and radionuclide effects of amlodipine in coronary artery disease.1990 · 8 citations