What question did this study set out to answer?

This research aims to construct a prognostic model for hepatocellular carcinoma by investigating palmitoylation-related genes.

February 2, 2026Open Access

Construction of a prognostic model and multidimensional analysis of hepatocellular carcinoma based on palmitoylation-related genes

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Key Points

This research aims to construct a prognostic model for hepatocellular carcinoma by investigating palmitoylation-related genes.
Analyzed single-cell and bulk transcriptomes of HCC epithelial cells
Investigated the regulatory network of palmitoylation in HCC
Developed a prognostic model based on gene expression data
Identified new molecular targets for HCC prognosis
Established a comprehensive regulatory network of palmitoylation in HCC cells
Provided methodological references for precision therapy in HCC

Abstract

This study is the first to analyze the regulatory network of palmitoylation in HCC epithelial cells by combining single-cell and bulk transcriptomes, providing new molecular targets and methodological references for HCC prognosis evaluation and precision therapy.

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Authors

Hui Zhang

IE University

Huan Su

IE University

Kaimei Xia

IE University

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IE University

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Construction of a prognostic model and multidimensional analysis of hepatocellular carcinoma based on palmitoylation-related genes

Key Points

Abstract

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