Comparative Effectiveness of Intratympanic Corticosteroids Versus Antibiotics in the Treatment of Meniere's Disease: A Review Study

Meniere's disease is an inner ear pathology characterized by recurrent episodes of vertigo, sensorineural hearing loss, a sensation of fullness in the ear, and tinnitus. It is estimated to occur at a rate of 15 individuals per 100,000 globally. Several recommendations exist for treating the disease, but there is no exact guideline to approach its management. In this study, we reviewed a decade of studies on the intratympanic approach to treating Meniere's disease which compared corticosteroids and antibiotics used on the condition. We found that the available data present conflicting evidence, and studies that investigated intratympanic gentamicin or dexamethasone did not demonstrate conclusive improvement in patient outcomes.