This review examines herbal nail lacquers' effectiveness for treating onychomycosis, suggesting a safer alternative to traditional methods.
Millions of people suffer from onychomycosis worldwide, a common fungal infection of the nails that frequently causes brittleness, thickness, and discoloration. Conventional treatments like oral antifungals and synthetic nail lacquers are usually linked to problems like systemic adverse effects, drug interactions, little nail penetration, and high relapse rates. Herbal nail lacquers, which combine plant-derived actives including tea tree oil, oregano oil, neem extract, Caesalpinia bonducella extract and coniferous resins with sophisticated formulation techniques, have become a viable substitute in recent years. These natural substances have broad-spectrum antifungal, anti-inflammatory, and anti-oxidant activities, and they frequently work through a variety of mechanisms which lowers the likelihood of resistance. Drug delivery, release sustainability, and patient compliance are all improved by the use of penetration enhancers, film-forming agents, and resins. Quality and therapeutic potential are guaranteed by evaluation factors such as drying time, adhesion, viscosity, content of active ingredients and antifungal activity. Herbal nail lacquers, with their low toxicity and good safety profiles, provide a practical, patient-friendly way to treat onychomycosis. This helps to overcome the drawbacks of traditional therapies and satisfy the increasing need for safe, efficient, and pleasing treatments.
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Aishwarya Hiremath1*, Samarth A. V.2, Atiya2, Shrushti S.2, Manikantha P. Garlpet2, Muhammed Mussamil A.2 (2026) studied this question.
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