Why the study?
Data on the impact of percutaneous edge-to-edge repair on right ventricular remodeling in symptomatic severe tricuspid regurgitation are scarce.
Does percutaneous edge-to-edge repair (TEER) improve tricuspid regurgitation and right ventricular remodeling in patients with symptomatic severe TR?
Population
44 symptomatic severe TR patients undergoing TEER
Comparison
Pre- vs post-TEER echocardiographic parameters
Design
Prospective, single-center observational study
Follow-up
3 months
Key result
Percutaneous edge-to-edge repair for symptomatic severe tricuspid regurgitation significantly reduced TR grade and RV basal diameter (48 to 44 mm; p=0.007) at 3 months.
Authors
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Short-term remodeling after TEER should not yet change practice; leaves open durability, clinical benefit, and need for randomized confirmation.
Observational (n=44)
No
Does percutaneous edge-to-edge repair (TEER) improve tricuspid regurgitation and right ventricular remodeling in patients with symptomatic severe TR?
TEER for symptomatic severe tricuspid regurgitation effectively reduces regurgitation and promotes favorable short-term right ventricular and annular remodeling at 3 months, despite a reduction in TAPSE.
Lopez et al. (2026) conducted an observational in symptomatic severe tricuspid regurgitation (n=44). Percutaneous edge-to-edge repair (TEER) was evaluated on Tricuspid regurgitation reduction and right ventricular remodeling. Percutaneous edge-to-edge repair for symptomatic severe tricuspid regurgitation significantly reduced TR grade and RV basal diameter (48 to 44 mm; p=0.007) at 3 months.