What question did this study set out to answer?

This research aims to clarify the role of POM121 in the progression of gastric cancer and its associated signaling mechanisms.

February 2, 20260 citations

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POM121 Drives Gastric Cancer Progression via the mTOR/p70S6K Signaling Axis.

HKHong-Beum KimChosun University SKSEONG-HUN KIMChosun University Hospital HLHye-Hwa LeeChosun University

Key Points

This research aims to clarify the role of POM121 in the progression of gastric cancer and its associated signaling mechanisms.
Examined the role of POM121 in gastric cancer progression
Analyzed p70S6K signaling pathways
Evaluated the effects on cell proliferation and invasion
POM121 enhances the proliferative capacity of gastric cancer cells
POM121 increases invasive behavior in gastric cancer
Identified POM121 as a potential prognostic biomarker and therapeutic target

Abstract

POM121 promotes GC progression by enhancing proliferative and invasive phenotypes through p70S6 kinase-mediated signaling. These findings establish POM121 as a novel oncogene, prognostic biomarker, and potential therapeutic target in GC.

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Cite This Study

Kim et al. (Sun,) studied this question.

synapsesocial.com/papers/6980fe9bc1c9540dea810cca https://doi.org/https://doi.org/10.21873/anticanres.17987

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