Neuroinflammation in the nerve roots and dorsal root ganglion decreases following 6 weeks of neural tissue management: PET/CT imaging findings in a patient with painful cervical radiculopathy

Ivo J. Lutke Schipholt; Michel W. Coppieters; Meghan A. Koop; Ronald Boellaard; Elsmarieke van de Giessen; Wilco C. Peul; P.R.A.M. Depauw; Bart N.M. van Berckel; Adriaan A. Lammerstma; Maqsood Yaqub; Gwendolyne G M Scholten-Peeters

doi:10.1016/j.msksp.2026.103502

January 1, 2026Musculoskeletal Science and PracticeOpen Access

Neuroinflammation in the nerve roots and dorsal root ganglion decreases following 6 weeks of neural tissue management: PET/CT imaging findings in a patient with painful cervical radiculopathy

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Key Points

This research aims to assess the changes in neuroinflammation after neural tissue management in cervical radiculopathy.
Conducted PET/CT imaging to evaluate neuroinflammation
Tracked changes in neuroinflammation in nerve roots and dorsal root ganglion
Involved a patient with painful cervical radiculopathy
Neuroinflammation reduced beyond the smallest detectable difference
Findings support the potential effectiveness of neural tissue management

Implication

Neural tissue management decreases neuroinflammation in cervical radiculopathy, suggesting potential for pain relief.

Abstract

Changes in neuroinflammation exceeding the smallest detectable difference can be measured following neural tissue management in a patient with painful cervical radiculopathy. A randomised trial to validate these findings is warranted.

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Cite This Study

Schipholt et al. (2026) studied this question.

synapsesocial.com/papers/6980fecbc1c9540dea8112a5 https://doi.org/10.1016/j.msksp.2026.103502

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Neuroinflammation in the nerve roots and dorsal root ganglion decreases following 6 weeks of neural tissue management: PET/CT imaging findings in a patient with painful cervical radiculopathy

Key Points

Implication

Abstract

Discussion

Cite This Study

Neuroinflammation in the nerve roots and dorsal root ganglion decreases following 6 weeks of neural tissue management: PET/CT imaging findings in a patient with painful cervical radiculopathy

Key Points

Implication

Abstract

Discussion

Cite This Study

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