Key result
Curcumin shows promise in protecting cardiomyocytes and enhancing vascular function despite inconsistent cholesterol results.
Why the study?
Curcumin is recognized for its therapeutic potential in cardiovascular diseases, but a comprehensive evaluation of its therapeutic effects, mechanisms of action, and safety was needed.
Does curcumin have therapeutic potential in cardiovascular diseases?
Does curcumin have therapeutic potential in cardiovascular diseases?
Curcumin shows promise as a complementary agent in CVD management, but requires large-scale clinical trials to validate efficacy and safety.
Supports adjunctive curcumin in CVD; leaves open efficacy and safety pending large RCTs.
Background Curcumin is recognized for its therapeutic potential in cardiovascular diseases (CVDs), with effects on cardiomyocytes, vascular function, and hypertrophy. Objective This review aims to evaluate curcumin's therapeutic effects, mechanisms of action, and safety in CVD management. Methods A comprehensive review of existing literature was conducted, focusing on curcumin's impact on ischemia, hypoxia, myocardial hypertrophy, fibrosis, and endothelial function. Results Curcumin protects cardiomyocytes, enhances vascular function, and exhibits inconsistent effects on cholesterol accumulation in macrophages. Conclusion While curcumin shows promise as a complementary agent in CVD management, further research, particularly large‐scale clinical trials, is essential to validate its efficacy and safety.
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Nourmohammad et al. (2026) conducted a review in Cardiovascular diseases. Curcumin was evaluated on Therapeutic effects, mechanisms of action, and safety. Curcumin protects cardiomyocytes and enhances vascular function, showing promise as a complementary agent in cardiovascular disease management.
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