Demonstrates METTL14's role in reducing neovascularization in proliferative retinopathy, suggesting a new treatment pathway.
This study suggests that METTL14-mediated m⁶A modification is a pivotal step in regulating the pathogenesis of retinal neovascularization. Therefore, METTL14 might be introduced as a promising therapeutic strategy for the management of PR. However, our findings are limited by the types of clinical samples, and further validation in larger clinical cohorts is required.
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Guan et al. (2026) studied this question.
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