Mendelian randomization study: investigating the causal impact of Covid-19 on adverse pregnancy outcomes

Ruisi Tang; Weijie Guo; Ying Hu; Mengna Ma; Luying Xu; Y. Huang; Rui Cai; Y. Zhang

doi:10.1186/s12985-025-03058-1

January 30, 2026Virology JournalOpen Access

Mendelian randomization study: investigating the causal impact of Covid-19 on adverse pregnancy outcomes

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Key Points

This research aims to determine if Covid-19 is a causal risk factor for adverse pregnancy outcomes (APOs).
Utilized mendelian randomization design to assess genetic evidence.
Analyzed data connecting Covid-19 and pregnancy outcomes.
Focused on the effects of Covid-19 infection during pregnancy.
Findings support Covid-19 as a significant causal risk factor for adverse pregnancy outcomes.
Suggests the need for prioritizing therapies for pregnant women infected with Covid-19.

Implication

Mendelian randomization study finds Covid-19 causes adverse pregnancy outcomes, highlighting urgent interventions for pregnant women.

Abstract

Our study uncovered genetic evidence supporting COVID-19 as a causal risk factor for APOs, suggesting the importance of prioritizing therapeutic interventions for pregnant women infected with COVID-19 within society.

Discussion

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Cite This Study

Tang et al. (2026) studied this question.

synapsesocial.com/papers/6980fefbc1c9540dea81191e https://doi.org/10.1186/s12985-025-03058-1

View Full Paper

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Mendelian randomization study: investigating the causal impact of Covid-19 on adverse pregnancy outcomes

Key Points

Implication

Abstract

Discussion

Cite This Study

Mendelian randomization study: investigating the causal impact of Covid-19 on adverse pregnancy outcomes

Key Points

Implication

Abstract

Discussion

Cite This Study

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