Novel additive-free method synthesizes 2,4-disubstituted oxazoles in mild conditions, suggesting a more accessible approach for chemists.
A novel, additive-free method has been developed for synthesizing 2,4-disubstituted oxazoles via thiourea-mediated cyclization of substituted 2-oxo-2-phenylethyl acetates. This approach utilizes readily available thiourea and α-acyloxy ketones under mild conditions...
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Wang et al. (2026) studied this question.
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