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February 5, 2026Digestive and Liver Disease0 citationsOpen Access

Esophageal, gastric and duodenal Crohn’s disease in the biologic era: Results from a retrospective observational nationwide study of GETECCU

ALAlicia López-GarcíaHospital del Mar Research InstituteCFCristina Suárez FerrerHospital Universitario La PazCMCarlos Maroto-MartínHospital Universitario Río Hortega

Key Points

  • This study investigates whether upper gastrointestinal involvement in Crohn’s disease affects the need for immunosuppressive therapy.
  • Conducted a retrospective observational study across a nationwide cohort.
  • Analyzed therapeutic needs in patients with esophageal, gastric, and duodenal Crohn's disease.
  • Compared immunosuppressive requirements with those of other Crohn's disease patients.
  • No significant variation in immunosuppressive therapy needs was observed for patients with upper GI involvement.
  • Therapeutic requirements remained consistent across different types of Crohn's disease.

Abstract

Upper gastrointestinal involvement in adult CD does not appear to alter immunosuppressive therapeutic needs compared with ECD requirements.

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Cite This Study

López-García et al. (2026) studied this question.

synapsesocial.com/papers/69843360f1d9ada3c1fb06behttps://doi.org/10.1016/j.dld.2025.12.034
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