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February 5, 2026Clinica Chimica Acta2 citationsOpen Access

Bioequivalence of C-reactive protein in fingerprick blood and serum measured using the point-of-care LumiraDx test for tuberculosis diagnosis in exposed contacts

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ACArthur ChiwayaSAShima M. AbdulgaderNHNorbert Heinrich

Key Points

  • The aim is to evaluate if C-reactive protein measurements are similar in fingerprick blood and serum using the LumiraDx test.
  • Measured C-reactive protein levels in fingerprick blood and serum samples
  • Compared the results between the two methods
  • Analyzed sensitivity of the tests for tuberculosis diagnosis
  • C-reactive protein levels correlate closely between fingerprick blood and serum
  • Stored serum can be reliably used for C-reactive protein measurement
  • High sensitivity results in a higher rate of false-positive screenings

Abstract

LumiraDx CRP readouts on fingerprick blood and serum correlate closely. Stored serum can be used for LumiraDx CRP measurement. High sensitivity methods increase the proportion of people who screen false-positive.

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Cite This Study

Chiwaya et al. (2026) studied this question.

synapsesocial.com/papers/69843360f1d9ada3c1fb06c5https://doi.org/10.1016/j.cca.2026.120876
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