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January 31, 2026VaccineOpen Access

Accuracy of ICD and SNOMED search strategies for adverse events following COVID-19 vaccination: Analysis of hospital administrative data

Timothy Kenealy Nelson Aguirre-Duarte Richard H. Roxburgh Gordon Royle Bryan Mitchelson Joan Ingram Nicky Williams Helen Petousis-Harris

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Key Points

The aim is to assess the accuracy of ICD and SNOMED codes for identifying adverse events related to COVID-19 vaccination.
Analyzed hospital administrative data using ICD and SNOMED codes
Assessed positive predictive values (PPVs) for various codes
Identified limitations in estimating missed cases due to coding inaccuracies
Many codes were found to lack sufficient accuracy in identifying targeted adverse events
No combinations of codes were assessed for their PPVs
Specific case-by-case evaluations of codes were emphasized.

Implication

Analysis evaluates coding accuracy for adverse events after COVID-19 vaccination, indicating variability in effectiveness.

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Cite This Study

Kenealy et al. (2026) studied this question.

synapsesocial.com/papers/69843360f1d9ada3c1fb0727 https://doi.org/10.1016/j.vaccine.2026.128275

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