Longitudinal Association Between Disc Hemorrhage and Primary Open-Angle Glaucoma Progression: A Systematic Review and Meta-Analysis

Chelsea Qiu Lin Tan; Vipin Kumar; Bee Choo Tai; Nicole Shu-Wen Chan; Wanxian Katherine Lun; Yih-Chung Tham; Victor Teck Chang Koh

doi:10.1080/09286586.2025.2568395

February 2, 2026Ophthalmic Epidemiology

Longitudinal Association Between Disc Hemorrhage and Primary Open-Angle Glaucoma Progression: A Systematic Review and Meta-Analysis

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Key Points

The research aims to analyze how disc hemorrhage (DH) affects the progression of primary open-angle glaucoma (POAG).
Conducted a systematic review of existing studies
Performed a meta-analysis to quantify the relationship between DH and POAG progression
Analyzed outcomes related to retinal nerve fibre layer thinning and visual field loss
Baseline DH is significantly linked to increased progression of POAG
Patients with DH need closer monitoring due to higher risk of vision loss
Findings suggest DH as a critical predictor for NTG (normal tension glaucoma)

Implication

Systematic review highlights disc hemorrhage's role in monitoring glaucoma progression, indicating potential intervention needs.

Abstract

DH is an important predictor for POAG progression, particularly for NTG. The presence of baseline DH in POAG patients may warrant closer monitoring of retinal nerve fibre layer thinning and visual field loss.

Discussion

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Cite This Study

Tan et al. (2026) studied this question.

synapsesocial.com/papers/698433e9f1d9ada3c1fb1718 https://doi.org/10.1080/09286586.2025.2568395

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Longitudinal Association Between Disc Hemorrhage and Primary Open-Angle Glaucoma Progression: A Systematic Review and Meta-Analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Longitudinal Association Between Disc Hemorrhage and Primary Open-Angle Glaucoma Progression: A Systematic Review and Meta-Analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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