Helicobacter pylori Eradication Rates among Patients Undergoing Endoscopy Remain Stagnant Despite Evolving Clinical Practice Patterns

Although guidelines suggest querying prior antibiotic exposures before selecting H pylori therapy, our findings emphasize that alternative methods to improve eradication rates may be important. Although practice patterns shifted to use more metronidazole-based therapy, as currently suggested as first-line H pylori therapy in the United States, this change was not associated with an overall improvement in eradication rates.