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February 5, 20260 citationsOpen Access

Assessment of Antioxidant Activity and Bioactive Compounds in Papaya Leaves Extracts

Assessment of antioxidant activity and bioactive compound identification of methanol and petroleum ether extracts of male Papaya Leaves (Carica papaya L.) From Indonesia

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Authors

JJJunairiah JunairiahECEricha Fajar CahyaniEUEdy Setiti Wida Utami

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Overview

Evaluates antioxidant activity and identifies bioactive compounds in papaya leaves, suggesting potential for natural wellness products.

Key Points

  • The research aims to evaluate the antioxidant activity and identify bioactive compounds in extracts of papaya leaves.
  • Extraction using maceration method with methanol and petroleum ether solvents.
  • Assessment of antioxidant activity via DPPH assay.
  • Identification of bioactive compounds through phytochemical screening and GC-MS analysis.
  • Methanol extract shows weak antioxidant activity (IC50: 280.319 ppm).
  • Petroleum ether extract demonstrates moderate antioxidant activity (IC50: 142.565 ppm).
  • GC-MS identifies 26 bioactive compounds in methanol extract, with Neophytadiene being the most abundant.
  • Petroleum ether extract contains 18 bioactive compounds, with Hexadecanoic acid-methyl ester as the major component.

Cite This Study

Junairiah et al. (2025) studied this question.

synapsesocial.com/papers/698434b4f1d9ada3c1fb32fehttps://doi.org/10.5281/zenodo.18455925
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Also Consider

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  1. 1Phytochemical Analysis, Antioxidant Activity, and Inhibition of Digestive Enzymes of Carica papaya L. Leaf2026 · 1 citations
  2. 2EFFECT OF EXTRACTION SOLVENT AND EXTRACTION METHOD ON BIOACTIVE COMPOUNDS FROM DIFFERENT PARTS OF CARICA PAPAYA L.2024
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  4. 4Antioxidant, antibacterial activity, and phytochemical characterization of Carica papaya flowers2020 · 83 citations
  5. 5Comparative evaluation of methanol and water extracts: Antioxidant activity and total phenolic content of ten papuan medicinal plants2026