A challenging case diagnosed via ultrasound-guided fine-needle aspiration biopsy demonstrates the importance of accurate cytology in suspicious neck masses.
We report a rare case of salivary duct carcinoma (SDC) in a 67‐year‐old male who presented with a rapidly enlarging, ill‐defined left upper neck mass, accompanied by both cervical and axillary lymphadenopathy. Initial punch biopsy of the neck mass suggested metastatic breast carcinoma. However, ultrasound‐guided fine‐needle aspiration (US‐FNA) and comprehensive immunohistochemical analysis, in conjunction with radiologic findings, confirmed the diagnosis of SDC. This case highlights the diagnostic challenges of SDC and reinforces the pivotal role of US‐FNA cytology in establishing a definitive diagnosis while minimizing invasive procedures.
No takes yet. Share an insight, caveat, or question.
Khetan et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: