Nanofluidic-based Electrochemical Pump for Remotely Controlled, On-Demand Drug Delivery

Marco Maria Paci; Nicola Di Trani; Paolo Bolla; Fabiana Del Bono; Takuma Yoshikawa; Isaac Tichy; Patrick Stayton; Alessandro Grattoni

doi:10.1039/d5lc00708a

January 1, 2026Lab on a Chip

Nanofluidic-based Electrochemical Pump for Remotely Controlled, On-Demand Drug Delivery

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Key Points

The aim is to develop a novel electrochemical drug delivery system using nanofluidic membranes for customized therapy.
Designed a nanofluidic membrane-based electrochemical pump.
Tested the system for on-demand drug release through an implantable setup.
Assessed the tunable release profiles under various conditions.
Demonstrated effective control over drug release rates.
Achieved personalized release profiles according to therapeutic needs.
Showed potential for remote operation of the delivery system.

Implication

Implantable systems deliver drugs on-demand in individuals, suggesting personalized medical treatments could improve outcomes.

Abstract

Implantable drug delivery systems offer the promise of on-demand, tunable release profiles tailored to individual therapeutic needs. Here, we present a nanofluidic membrane-based electrochemical delivery system that leverages controlled in...

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Cite This Study

Paci et al. (2026) studied this question.

synapsesocial.com/papers/698435c9f1d9ada3c1fb4fec https://doi.org/10.1039/d5lc00708a

View Full Paper

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Nanofluidic-based Electrochemical Pump for Remotely Controlled, On-Demand Drug Delivery

Key Points

Implication

Abstract

Discussion

Cite This Study

Nanofluidic-based Electrochemical Pump for Remotely Controlled, On-Demand Drug Delivery

Key Points

Implication

Abstract

Discussion

Cite This Study

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