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February 5, 2026Rapid Communications in Mass Spectrometry0 citations

Development of an Atmospheric‐Pressure Photoionization Source for VOC Detection With a Miniature High‐Pressure Mass Spectrometer

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ARAlan M. RowlandSSStephen E. SmithEVE. F. Vandergriff

Key Points

  • The research aims to enhance the sensitivity and selectivity of VOC detection using a portable mass spectrometer.
  • Developed an atmospheric pressure photoionization (APPI) source for a miniature high-pressure mass spectrometer.
  • Utilized a VUV lamp in a custom 3D-printed apparatus.
  • Investigated and optimized the effects of pressure, RF voltage, aperture voltage, and humidity on performance.
  • Achieved linearity in detection for benzene, toluene, ethylbenzene, and m-xylene from 25 to 500 ppbV.
  • Demonstrated functionality at 0.8 Torr using ambient air as the buffer gas without the need for preconcentration.

Abstract

ABSTRACT With the goal of sensitive, selective, targeted, and portable VOC quantification, an atmospheric pressure photoionization (APPI) source was developed for a miniature high pressure mass spectrometer, the MX908. The APPI source consists of a VUV lamp that was encased in a custom 3D‐printed apparatus. Using m ‐xylene as the testing standard, the effects of pressure, axial RF voltage, aperture voltage, and humidity on the instrument were investigated and optimized. Operating at 0.8 Torr with ambient air as the buffer gas, the instrument showed linearity from 25 to 500 ppbV for benzene, toluene, ethylbenzene, and m ‐xylene without preconcentration.

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Cite This Study

Rowland et al. (2026) studied this question.

synapsesocial.com/papers/698435d5f1d9ada3c1fb50f2https://doi.org/10.1002/rcm.70050
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