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February 5, 2026Advanced Science2 citationsOpen Access

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

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XSXiaofei ShiZLZhijiao LiXMXin Ma

Key Points

  • This review investigates the relationship between vasculitis and malignancies, focusing on clinical characteristics and mechanisms.
  • Systematic examination of epidemiological patterns
  • Integration of relevant case reports
  • Analysis of mechanistic studies across vasculitic subtypes
  • Identifies clinical characteristics of tumor-associated vasculitis
  • Summarizes pathogenic mechanisms across vasculitic subtypes
  • Highlights practical recommendations for rheumatologists and oncologists

Abstract

ABSTRACT This review systematically examines the association between vasculitis and malignancies by summarizing the risk of tumor‐associated vasculitis, their clinical characteristics, and proposed pathogenic mechanisms across different vasculitic subtypes. Relevant case reports and mechanistic studies are integrated to provide a comprehensive overview of this entity. The findings offer practical value for rheumatologists in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, and for oncologists in improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision‐making and risk management.

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Cite This Study

Shi et al. (2026) studied this question.

synapsesocial.com/papers/698435f0f1d9ada3c1fb55d2https://doi.org/10.1002/advs.202521056
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