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Observational report reveals improved ventricles and prolonged seizure-free interval in a young patient with Chiari II malformation and severe brain issues, indicating treatment success.
Chiari II malformation is commonly associated with hydrocephalus requiring early cerebrospinal fluid (CSF) diversion and may coexist with complex supratentorial developmental abnormalities. As a result, patients with severe congenital structural brain anomalies and long-term ventriculoperitoneal (VP) shunting often experience neurodevelopmental impairment and are at increased risk of epilepsy. We report a 17-year-old girl with Chiari II malformation, repaired myelomeningocele, and ventriculoperitoneal shunting since birth (revision at five years of age), demonstrating marked ventricular improvement over a 16-year interval and a prolonged seizure-free interval despite severe congenital supratentorial malformations.
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Khird et al. (2026) studied this question.
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