Pulse Entdecken nav.journalClub Debatten Trends Forschende Zeitschriften

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Start Entdecken nav.journalClub Trends

⌘+K

The double face of IL-1β in lung cancer | Synapse

February 6, 2026Open Access

View Full Paper

The double face of IL-1β in lung cancer

CRCédric RébéUniversity of Geneva APAnaïs PerrichetCentre Georges François Leclerc FGFrançois GhiringhelliUniversité Claude Bernard Lyon 1

Key Points

This research investigates the dual role of IL-1β in lung cancer growth and treatment responses.
Analyzed the effects of IL-1β on lung cancer growth in human and mouse models.
Examined interaction with chemotherapy and immune checkpoint inhibitors.
Assessed resistance mechanisms associated with IL-1β.
IL-1β promotes lung cancer growth in both humans and mice.
In the context of standard treatments, IL-1β can help overcome therapeutic resistance.

Abstract

Interleukin (IL)-1β is known to promote lung cancer growth in both humans and mice. However, in the context of the current standard of care, which includes chemotherapy and immune checkpoint inhibitors, IL-1β can overcome resistance.

KI fragen

Like

Bookmark

Share

View Full Paper

Cite This Study

Rébé et al. (Tue,) studied this question.

synapsesocial.com/papers/698584b78f7c464f23008272 https://doi.org/https://doi.org/10.1080/2162402x.2026.2622661

KI fragen

Like

Bookmark

Share

View Full Paper