Reshaping the oxidative stress microenvironment by Bionic chiral Cu-Phe (D/L) nanozymes for promoting osteoimmunomodulation and osteogenic differentiation

Key Points

• The research aims to explore how bionic chiral Cu-Phe nanozymes can reshape the oxidative stress microenvironment to promote bone healing.
• Utilized bionic chiral Cu-Phe (D/L) nanozymes to modify oxidative stress levels
• Assessed osteoimmunomodulation effects on bone cell behavior
• Analyzed the impact on osteogenic differentiation in inflammatory conditions
• Bionic chiral nanozymes significantly reduced oxidative stress levels
• Promoted osteogenic differentiation of stem cells in inflammatory environments
• Enhanced immunomodulatory effects leading to improved bone health outcomes