Investigation of 1D Silicon Photonic Structure for Detection Biomolecular Concentration

In this study, we investigate a silicon based three‐layer biomolecule photonic structure comprising silicon (Si) semiconductor layers at the outer boundaries and a central DNA/protein aqueous solution layer. Numerical simulations (PWE) were conducted to analyze the influence of protein/DNA concentration on the photonic properties at a wavelength of 400/310 nm. Results indicate that a gradual decrease in the PBG as protein concentration increases with bandgap values shifting at a concentration of 0.1 g/mL. The devised photonic sensor achieves low detection limits of 0.010 g/mL and 0.0083 g/mL, respectively, with high refractive index sensitivities of 0.052 RIU −1 for protein and 0.050 RIU −1 for DNA. These findings demonstrate the sensor's significant capacity for precise and effective biomolecular detection for compact and practical biosensing applications.