PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 6, 20260 citationsOpen Access

Robust Procedure for Handling Censored Data in Clinical Trials

View Full Paper
EBEric Boahen

Key Points

  • The aim is to develop a robust procedure for estimating parameters in survival analysis while addressing the challenges posed by censored data.
  • Developed a robust model for merging censored and uncensored values.
  • Specified appropriate distributions to enhance maximum likelihood estimation.
  • Utilized simulations to assess the optimal performance of the proposed model.
  • The robust model showed improved estimation accuracy compared to traditional methods.
  • Simulations indicated that the model is maximized despite the presence of censored values.

Abstract

Abstract One of the difficult aspect in parameter estimation in survival analysis is the presence of censored values in survival data When patients survival time are measured in continuous time interval, the censored values continue to create discrepancies in estimations since the stochastics realization of censored values are masked. For this reason, appropriate distributions must be specified before maximum likelihood is used. An optimal approach that merges both censored values and uncensored values is appreciable since asymptotically distributions are not normal. Robust model and efficient algorithms developed to enhance optimal performance in estimation. Simulations show that the optimal robust model is maximized.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Eric Boahen (2026) studied this question.

synapsesocial.com/papers/698585fe8f7c464f23009cdfhttps://doi.org/10.5281/zenodo.18477493
Ask AI
Helpful
Bookmark
Share
View Full Paper