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February 8, 2026BMC Gastroenterology1 citationsOpen Access

Diagnostic value of LPRI for assessing advanced liver fibrosis in patients with chronic hepatitis B and non-alcoholic fatty liver disease

MWMin WangHCHuaxiao ChenJYJiaEn Yang

Key Points

  • This research aims to evaluate the effectiveness of LPRI in diagnosing advanced liver fibrosis in patients with chronic hepatitis B and non-alcoholic fatty liver disease.
  • Evaluated the diagnostic accuracy of LPRI in a cohort with chronic hepatitis B and non-alcoholic fatty liver disease.
  • Compared LPRI results with traditional methods for fibrosis assessment.
  • Assessed the impact on reducing the need for liver biopsies.
  • LPRI accurately predicts advanced fibrosis and cirrhosis.
  • Significant reduction in diagnostic uncertainty when using LPRI.
  • LPRI potentially decreases the number of unnecessary liver biopsies.

Abstract

LPRI shows good value in predicting and excluding advanced fibrosis and cirrhosis in patients with CHB combined with NAFLD, and can reduce diagnostic uncertainty for advanced fibrosis, thereby decreasing unnecessary liver biopsies and improving screening efficiency.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6988270a0fc35cd7a8845f0ahttps://doi.org/10.1186/s12876-026-04645-4
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