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February 8, 2026Hand Therapy2 citationsOpen Access

Physical assessment and rehabilitation for neurogenic thoracic outlet syndrome (NTOS): A scoping review

JOJ O’SullivanCRChristian RushtonMBMarcus Bateman

Key Points

  • This review aims to identify and describe the components of physical assessment and rehabilitation for neurogenic thoracic outlet syndrome (NTOS).
  • Conducted a scoping review using four databases: MEDLINE, EMBASE, CINAHL, and Cochrane.
  • Followed PRISMA-ScR guidelines for data collection.
  • Used the TIDieR checklist to organize rehabilitation intervention data.
  • Twenty-nine studies met eligibility criteria out of 1381 screened.
  • NTOS provocation tests and palpation of structures were frequently reported assessment components.
  • Exercise was the most common rehabilitation intervention, particularly stretching and strengthening exercises targeting key muscles.

Abstract

Introduction Neurogenic Thoracic Outlet Syndrome (NTOS) is a complex condition that can be encountered in musculoskeletal and hand therapy services. Rehabilitation is recognised as the primary treatment for NTOS however, detail on rehabilitation components are poorly described. This scoping review aimed to identify and describe the physical assessment and rehabilitation components alongside clinical reasoning strategies that may aid therapists in the conservative management of adults with NTOS. Methods Four databases (MEDLINE, EMBASE, CINAHL and Cochrane) were searched, utilising the PRISMA-ScR guidelines. The Template for Intervention Description and Replication (TIDieR) checklist was used to organise data regarding rehabilitation interventions for NTOS. Results Twenty-Nine out of 1381 studies identified, met the eligibility criteria. NTOS Provocation tests (16/18 89%) were the most frequently described assessment components, followed by palpation of pertinent structures (11/18 61%) and assessment of posture (10/18 56%). ‘Decompressing the thoracic outlet’ was the main aim encountered for rehabilitation programmes. Exercise (17/19 90%) was the most frequent rehabilitation intervention identified, with stretching ( n = 15), strengthening ( n = 14) and neural mobility ( n = 7) exercises being most prevalent. The Scalenes and Pectoralis muscles ( n = 10) were the main targets for stretching whilst the Scapula ( n = 9), Trapezius and Serratus Anterior muscles ( n = 5) were the main targets for strengthening exercises. Other interventions identified included, posture improvement ( n = 13), manual therapy ( n = 10), adjuncts ( n = 8) and activity modification ( n = 7). Discussion The reporting of rehabilitation techniques for NTOS is generally poor, particularly regarding treatment intensity. There is an essential need for a standardised and reproducible rehabilitation intervention for NTOS to be developed.

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Cite This Study

O’Sullivan et al. (2026) studied this question.

synapsesocial.com/papers/698828100fc35cd7a884747ehttps://doi.org/10.1177/17589983251411877
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