Meta-analysis reveals high malignancy rates in incidental solitary pulmonary nodules, suggesting improved clinical strategies for high-risk populations.
This meta-analysis provides a comprehensive assessment of malignancy rates and risk factors in incidental SPNs. The high pooled malignancy rate should be interpreted considering the significant heterogeneity and the inclusion of a high proportion of retrospective studies and populations from high-risk regions. Nonetheless, these findings offer essential evidence for clinical risk stratification, supporting optimized follow-up and informed decision-making.
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Zheng et al. (2026) studied this question.
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