The bacterial lysate OM-85 Reduces Exacerbations and Oral Corticosteroid Use in Frequently Exacerbating Patients with T2-High Asthma: The OMREXA Real-World Evidence Study

Maria Elpida Cristopoulou; Lilia Panteli; John Moisidis; Ioannis Christopoulos; Amalia Tryphonidou; Antonios Christopoulos

doi:10.1016/j.rmed.2026.108695

February 1, 2026Respiratory MedicineOpen Access

The bacterial lysate OM-85 Reduces Exacerbations and Oral Corticosteroid Use in Frequently Exacerbating Patients with T2-High Asthma: The OMREXA Real-World Evidence Study

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Key Points

The analysis aims to evaluate the effectiveness of OM-85 in reducing asthma exacerbations in patients with T2-high asthma.
Post hoc analysis of real-world evidence data
Focus on frequently exacerbating patients with T2-high asthma
Comparison of exacerbation rates before and after OM-85 administration
Significant reduction in asthma exacerbations noted
Decreased reliance on oral corticosteroids observed
Support for OM-85 as a therapeutic option for T2-high asthma

Implication

Post hoc analysis supports OM-85's effectiveness in reducing asthma exacerbations and medication use in patients.

Abstract

This secondary post hoc analysis supports the therapeutic benefit of OM-85 in patients with T2-high asthma who have frequent exacerbations despite adherence to SoC asthma therapy.

Discussion

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Cite This Study

Cristopoulou et al. (2026) studied this question.

synapsesocial.com/papers/698978dff0ec2af6756e716d https://doi.org/10.1016/j.rmed.2026.108695

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The bacterial lysate OM-85 Reduces Exacerbations and Oral Corticosteroid Use in Frequently Exacerbating Patients with T2-High Asthma: The OMREXA Real-World Evidence Study

Key Points

Implication

Abstract

Discussion

Cite This Study

The bacterial lysate OM-85 Reduces Exacerbations and Oral Corticosteroid Use in Frequently Exacerbating Patients with T2-High Asthma: The OMREXA Real-World Evidence Study

Key Points

Implication

Abstract

Discussion

Cite This Study

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