Blue light-promoted 2 + 4 cycloaddition of phosphe-nes and N-acylimines: Highly diastereoselective access to 3,4-dihydro-1,5,2-oxazaphosphinine 2-oxides

Key Points

• The investigation aims to explore a blue light-promoted cycloaddition reaction for creating oxazaphosphinine derivatives.
• Utilized blue light to promote the reaction of phosphoryl diazomethanes and N-acylimines
• Assessed the yields and diastereoselectivity of the resulting products
• Conducted a tandem sequence involving Wolff rearrangement
• Achieved yields ranging from satisfactory to excellent based on reaction conditions
• Demonstrated excellent diastereoselectivity in the cycloaddition products
• Successfully synthesized 3,4-dihydro-1,5,2-oxazaphosphinine 2-oxides