Case-based review shows improved perfusion in symptomatic children with cerebral proliferative angiopathy, suggesting early surgical evaluation is beneficial.
Pediatric CPA often manifests with ischemia and diffuse, eloquent-intermixed vasculature. In symptomatic children with hypoperfusion, indirect revascularization is a reasonable strategy to enhance perfusion and reduce recurrent ischemic events. Aggregated evidence and our illustrative case suggest robust and durable outcomes following pial-based indirect bypass, supporting early multidisciplinary evaluation and individualized surgical consideration.
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Moskalik et al. (2026) studied this question.
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