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February 9, 20260 citations

Cerebral proliferative angiopathy in pediatric patients: case-based review with an illustrative case.

AMAnzhela D. MoskalikJMJonathan MoMSMonifa Sawyerr

Key Points

  • This research aims to explore the impact of indirect revascularization on pediatric patients with cerebral proliferative angiopathy.
  • Case-based review of pediatric patients with CPA
  • Evaluation of treatment outcomes following indirect revascularization
  • Assessment of perfusion levels and ischemic events
  • Improved perfusion noted in symptomatic children post-surgery
  • Reduction in recurrent ischemic events observed
  • Robust and durable outcomes following pial-based bypass procedures

Abstract

Pediatric CPA often manifests with ischemia and diffuse, eloquent-intermixed vasculature. In symptomatic children with hypoperfusion, indirect revascularization is a reasonable strategy to enhance perfusion and reduce recurrent ischemic events. Aggregated evidence and our illustrative case suggest robust and durable outcomes following pial-based indirect bypass, supporting early multidisciplinary evaluation and individualized surgical consideration.

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Cite This Study

Moskalik et al. (2026) studied this question.

synapsesocial.com/papers/698979e9f0ec2af6756e7f7chttps://doi.org/10.1007/s00381-026-07129-8
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