Systematic review evaluates caffeine's effects on bronchiolitis-related apnea, suggesting a reduction in respiratory support duration.
• This is the first systematic review with meta-analysis evaluating caffeine in BRA, showing no significant improvement in major clinical outcomes, but suggesting a possible reduction in overall respiratory support duration. • The study identifies critical methodological limitations in the existing literature, including heterogeneous apnea definitions and non-standardized caffeine dosing, and proposes a framework for future controlled studies.
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Brossier et al. (2026) studied this question.
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