Answers are grounded in this paper and cite their sources.
This multicenter study compares susceptibility testing methods for MRSA, highlighting challenges in accurate classification and implications for treatment.
This study demonstrates frequent clustering of MRSA isolates within the EUCAST-defined area of technical uncertainty, defined for ceftobiprole as an MIC of 2 mg/L, corresponding to the susceptibility breakpoint and its adjacent zone where categorization is inherently unreliable. Methodological limitations of agar dilution and Etest further increase the risk of misclassification and potential failure to detect resistance. These findings underscore the need for optimized susceptibility testing strategies and refined interpretive guidance to support accurate clinical use of ceftobiprole.
No takes yet. Share an insight, caveat, or question.
Zhu et al. (2026) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: