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A systematic review evaluates interventions for decolonizing resistant bacteria, suggesting standardization in approaches.
FMT and SDD are promising interventions for CRE decolonisation; with FMT also showing benefit in VRE. The durability of SDD effects appears limited, with significant risk of promoting resistance. Future studies should standardise endpoints, evaluate combination approaches, and explore bacteriophage therapy. We suggest implementing uniform terminology with "provisional clearance" as a descriptor for eradication at 1-month post-intervention and "enduring clearance" following continuous eradication for 6 months.
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McCafferty et al. (2026) studied this question.
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