Case report shows invasive fungal infections causing pneumonia in an immunocompetent dengue patient, indicating the need for aggressive treatment.
Invasive fungal infection (IFI) simultaneously due to three fungi is rare. IFI caused by two fungal agents is relatively commoner in transplant patients. Most common IFI worldwide is candidiasis, whereas in India, aspergillosis and mucormycosis infections are commoner. Severe dengue viral infection has been linked with invasive fungal infections. Following case report exemplifies more than two fungi can together cause pneumonia as confirmed by similar findings in 3 respiratory samples from the dengue shock syndrome patient. High clinical suspicion and prompt initiation of aggressive, high-dose, guideline-recommended antifungal therapy is essential at the slightest doubt of mucormycotic pneumonia.
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Tripathy et al. (2026) studied this question.
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