Pulse nav.journalClub Tendências Explorar Pesquisadores

Download the App

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

© Synapse Social LLC, 2026

Política de privacidade

Início Explorar nav.journalClub Tendências

⌘+K

JAK2 pathogenic variants in ischemic stroke: low prevalence and pre-screening model. | Synapse

February 10, 2026

JAK2 pathogenic variants in ischemic stroke: low prevalence and pre-screening model.

Key Points

Investigate the prevalence of JAK2 mutations in ischemic stroke and develop a predictive model.
Analyzed JAK2 V617F mutation prevalence in ischemic stroke cases.
Developed a predictive model to identify at-risk individuals.
Employed a precision medicine approach to genetic screening.
Found JAK2 V617F mutation prevalence at 0.4% in ischemic stroke patients.
Developed a model that may reduce reliance on extensive genetic testing.

Abstract

Despite low prevalence (0.4%), JAK2 V617F mutation represents a clinically actionable stroke subtype with distinct pathophysiology. The prediction model offers a precision medicine approach, potentially reducing the need for comprehensive genetic testing.

Like

Bookmark

Share

View Full Paper

Like

Bookmark

Share

View Full Paper

Cite This Study

Zhao et al. (Sat,) studied this question.

synapsesocial.com/papers/698acad77c832249c30ba51c https://doi.org/https://doi.org/10.1007/s00415-026-13658-8