SHIP-1 Modulation in Experimental Allergic Conjunctivitis: Impact on CD4 + T Cell Migration

Key Points

• The central aim is to explore how SHIP-1 activation affects CD4+ T cell migration in experimental allergic conjunctivitis.
• Activation of SHIP-1 was studied in the context of experimental allergic conjunctivitis.
• Effects on CD4+ T cell migration were observed.
• Modulation of the PI3K/AKT/mTOR signaling pathway was analyzed.
• SHIP-1 activation suppressed pathogenic CD4+ T cell migration.
• Modulation of the PI3K/AKT/mTOR pathway was confirmed.
• The findings highlight the anti-inflammatory role of SHIP-1 activators.