Structural MRI study shows salience network influences exercise dependence and depression in older adults, suggesting a treatment target.
In older adults, increased structural connectivity within the salience network may amplify impulsive and reward-driven cravings for exercise and the ability to perceive emotional states such as depression. These findings indicate that the salience network could serve as a potential target for preventing and treating exercise dependence in the elderly population.
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Zhang et al. (2026) studied this question.
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