Safety and efficacy of botulinum toxin in Human T-Lymphotropic Virus-1-Associated Myelopathy/Tropical Spastic Paraparesis: A randomized clinical trial

Key Points

• The research aims to assess the safety and efficacy of botulinum toxin in treating symptoms associated with HAM/TSP.
• Conducted a randomized clinical trial
• Administered botulinum toxin to participants with HAM/TSP
• Evaluated spasticity, pain, functioning level, and quality of life post-injection.
• Botulinum toxin was found to be safe for participants with HAM/TSP.
• The initial dose did not improve symptoms such as spasticity and pain after three months.
• Quality of life did not significantly change following treatment.