Demonstrates efficient dehalogenation of heteroaryl halides using triethylsilane, implying practical applications in organic synthesis.
An efficient dehalogenation reaction of α-substituted halogenated heterocycles catalyzed by Pd/C with triethylsilane (TES) was developed. This study explores the catalytic dehalogenation of N-heteroaryl halides using a Pd/C-K 2 CO 3 system, with TES serving as the hydrogen source under air conditions (air and moisture). The reaction conditions are compatible with various functional groups with good to excellent yields.
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Yu et al. (2026) studied this question.
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