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February 12, 2026Open Research EuropeOpen Access

ERGA-BGE reference genome of Hirudo verbana, a once neglected freshwater haematophagous European medicinal leech

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Authors

AMAlejandro Manzano-MarínABAstrid BohneRMRita Monteiro

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Overview

Genome assembly reveals subspecific diversity in Hirudo verbana, implying potential for microbiota research.

Key Points

  • To assemble a reference genome of Hirudo verbana for understanding its biodiversity and gut microbiota.
  • Conducted molecular and taxonomic analyses to uncover subspecific diversity.
  • Assembled the genome into two haplotypes, designating one as the reference.
  • Created 14 chromosomal pseudomolecules, including the mitogenome.
  • Primary haplotype assembly covers 0.18 Gb consisting of 277 contigs and 27 scaffolds.
  • Contig and scaffold N50 values were determined to be 1.3 Mb and 13.4 Mb, respectively.
  • Leech's limited microbiome suggests a valuable model for gut microbiota studies.

Cite This Study

Manzano-Marín et al. (2026) studied this question.

synapsesocial.com/papers/698d6e7b5be6419ac0d543a1https://doi.org/10.12688/openreseurope.21672.2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blood Relatives: Linking Evolutionary History and Conservation of Medicinal Leeches ( <i>Hirudo</i> spp.)2026 · 1 citations
  2. 2The genome sequence of the freshwater leech, Erpobdella octoculata (Linnaeus, 1758) (Hirudinida: Erpobdellidae)2025
  3. 3Intraspecies Molecular DNA Polymorphism and Threat of Hirudo orientalis2024
  4. 4Diversity of hirudin and hirudin-like factor genes in the North-African medicinal leech, Hirudo troctina2024
  5. 5ERGA-BGE reference genome of Holothuria (Platyperona) sanctori: a sea cucumber from the Mediterranean Sea2026