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February 13, 2026BMC Infectious Diseases0 citationsOpen Access

Predictors of Brucella spp. bacteraemia at admission among adults with brucellosis: a two-centre retrospective cohort study in Ningxia, China

FZFeng-Fu ZhanZhongshan Hospital of Xiamen University SHShi-Shen HuThe Fourth People's Hospital of Ningxia Hui Autonomous Region FXFa-Guang XuThe Fourth People's Hospital of Ningxia Hui Autonomous Region

Key Points

The study aims to identify predictors of Brucella spp. bacteraemia at admission among adults with brucellosis.
Retrospective cohort design
Data collected from two centers in Ningxia, China
Development of a clinical-laboratory model using admission data
The clinical-laboratory model demonstrated excellent discrimination for early bacteraemia risk
The model showed acceptable internal calibration
Further external validation in other endemic areas is warranted

Abstract

A combined clinical-laboratory model based on readily available admission data showed excellent discrimination for early risk stratification of bacteraemia among adults with brucellosis, with acceptable internal calibration, and warrants external validation in other endemic, resource-limited settings.

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