Combined Triflow, deep breathing, and coughing exercises significantly improved postoperative oxygen saturation and FEV₁/FVC ratio compared to Triflow alone in mitral valve replacement patients, with no pulmonary complications observed in either group.
RCT (n=60)
single-blind (participants blinded, researcher unblinded)
simple randomization by coin flip
No
Does combined Triflow, deep breathing, and coughing exercises improve postoperative pulmonary function and reduce complications in adult patients undergoing mitral valve replacement?
Combining deep breathing and coughing exercises with standard Triflow use significantly improves postoperative pulmonary function, reduces pain, and shortens time to mobilization after mitral valve replacement.
Effect estimate: Significant improvements in SpO₂ at T1 (p=0.009; 95% CI 0.46–3.14), T2 (p<0.001; 95% CI 1.57–3.43), and T3 (p<0.001; 95% CI 2.72–4.54); Increased FEV₁/FVC ratio at discharge (p<0.001; 95% CI 4.46–6.41); No pulmonary complications in either group
ClinicalTrials.gov Identifier NCT06997224 (First registered on 15 May 2025).
Akıncı et al. (2026) conducted an RCT in mitral valve replacement surgery (n=60). Combined Triflow, deep breathing, and coughing exercises vs. Triflow alone was evaluated on Postoperative pulmonary function parameters SpO₂ and FEV₁/FVC, and pulmonary complications (Significant improvements in SpO₂ at T1 (p=0.009; 95% CI 0.46–3.14), T2 (p<0.001; 95% CI 1.57–3.43), and T3 (p<0.001; 95% CI 2.72–4.54); Increased FEV₁/FVC ratio at discharge (p<0.001; 95% CI 4.46–6.41); No pulmonary complications in either group). Combined Triflow, deep breathing, and coughing exercises significantly improved postoperative oxygen saturation and FEV₁/FVC ratio compared to Triflow alone in mitral valve replacement patients, with no pulmonary complications observed in either group.