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Genomic analysis reveals increased beta-lactam nonsusceptibility in Streptococcus pneumoniae, suggesting significant genetic influences.
We revealed that the widespread nonsusceptibility to multiple beta-lactams among SP isolates circulating in central Vietnam was primarily driven by the dynamics of the pbp2x gene. However, the nonsusceptible pbp2x allele had little effect on clinical outcome.
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Fujii et al. (2026) studied this question.
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