Key result
Higher CRP/HDL ratio is linked to increased stroke risk, with stronger associations in normoglycemic adults.
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Associates higher C-reactive protein/HDL cholesterol ratio with increased stroke risk in Chinese adults, suggesting implications for risk assessment.
Higher CHR was associated with an increased risk of stroke in Chinese adults, with heterogeneity across glycemic status, showing stronger and nonlinear (J-shaped) associations in NGR than in diabetes. CHR demonstrated limited discriminative ability for stroke, suggesting its utility may lie in risk stratification rather than standalone prediction.
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Huang et al. (2026) studied this question. Higher C-reactive protein/HDL cholesterol ratio was associated with increased stroke risk in Chinese adults, showing a stronger J-shaped association in normal glucose regulation than in diabetes.
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