Understanding the Humanistic Burden of Metabolic Dysfunction-Associated Steatohepatitis Liver Disease in the US Population: Age/Sex Stratified Analysis of Morbidity and Mortality

The analysis shows that mortality is a greater burden than morbidity for MASH, and that owing to the insidious nature of the disease, burden is likely to be concentrated in the seventh to eighth decade of life (60-79-year-olds). The burden for females is higher than for males, without differential incidence, owing to women's longevity. The incidence of MASH is expected to rise owing to the increasing prevalence of obesity and diabetes in the population.